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Keggin Heteropolyacid Catalyzed Synthesis of Isoxazolo[5,4-d]pyrimidine-4,6(5H,7H)-diones at Room Temperature
Authors:Bamoharram Fatemeh F  Roshani Mina  Heravi Majid M  Mahdavi Masoumeh  Javid Ali  Emampour Jalal Sh
Affiliation:Bamoharram1 Fatemeh F,Roshani Mina,Heravi Majid M,Mahdavi Masoumeh,Javid Ali,Emampour Jalal Sh
Abstract:Isoxazolo[5,4‐d]pyrimidine‐4,6(5H,7H)diones 2a – 2f have been synthesized from the reaction of ethyl 5‐amino‐3‐methyl‐4‐isoxazole carboxylate ( 1 ) with aryl isocyanates in the presence of Keggin heteropolyacid H3[PW12O40] as a green solid acid catalyst at room temperature in a one‐pot process in good yields.
Keywords:isoxazolopyrimidine  cyclization  heteropolyacid  Keggin  catalyst
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