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枸橼酸氢钾钠溶解肾集合管结晶的临床观察
引用本文:黄辉,王彤,陈洁,肖龙,黄湖辉,王景峰,徐安平,吕军,王华敏. 枸橼酸氢钾钠溶解肾集合管结晶的临床观察[J]. 中国临床实用医学, 2008, 2(9): 1-2
作者姓名:黄辉  王彤  陈洁  肖龙  黄湖辉  王景峰  徐安平  吕军  王华敏
作者单位:1. 中山大学附属第二医院,510120
2. 广州医学院附属第二医院
摘    要:目的探讨枸橼酸氢钾钠溶解。肾集合管结晶的疗效。方法筛选22例肾集合管结晶患者,给予枸橼酸氢钾钠10g/d,比较治疗前后症状和实验室检查的变化。结果治疗后,患者腰痛和尿路刺激症状明显减少(86.4%vs13.6%,68.2%VS4.5%,P〈O.05),同时尿红细胞和白细胞大幅减少,肾脏多普勒显示集合管结晶有明显改善(95.5%vs9.1%,68.2%vs13.6%,100%掷22.7%,P〈0.05)。结论枸橼酸氢钾钠能有效溶解肾集合管结晶,减少肾结石的发生。

关 键 词:枸橼酸氢钾钠  肾脏  结晶

The clinic study of potassium sodium hydrogen citrate on collecting duct crystal
Affiliation:HUANG Hui, WANG Tong, CHEN Jie, et al( The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou 510120, China )
Abstract:Objective To study the effect of potassium sodium hydrogen citrate on collecting duet crystal.Methods 22 patients with collecting duct crystal were applied potassium sodium hydrogen citrate (10 g/d),clinical symptom and lab examination were compared after therapy.Results Lumbago and the incidence of urinary symptom were lower(86.4% vs 13.6% ,68.2% vs 4.5% ,P <0.05) ,with the decrease of RBC and WBC in urine ,and collecting duct crystal in doppler scan (95.5% vs9.1%,68.2% vsl 3.6%,100% vs22.7%,P <0.05).ConclusionPotassium sodium hydrogen citrate is an effective therapy for collecting duct crystal,and it prevents the formation of renal stone.
Keywords:Potassium  sodium hydrogen  citrate  Kidney  Crystal
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