| 盐酸西替利嗪的合成与应用 |
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| 引用本文： | 谢正平,李忠铭,尤庆亮,喻宗沅.盐酸西替利嗪的合成与应用[J].化学与生物工程,2009,26(1). |
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| 作者姓名： | 谢正平 李忠铭 尤庆亮 喻宗沅 |
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| 作者单位： | 1. 湖北省化学研究院,湖北,武汉,430074
2. 江汉大学化学与环境工程学院,湖北,武汉,430056 |
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| 摘 要： | 盐酸西替利嗪是第二代H1 受体拮抗剂,是目前国际上最畅销的抗过敏药物之一.介绍了盐酸西替利嗪的安全性、疗效、最新的临床应用;重点评述了盐酸西替利嗪由四个起始反应原料出发的合成路线及其优缺点.
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| 关 键 词： | 盐酸西替利嗪 合成与应用 抗过敏 |
Synthesis and Application of Cetirizine Dihydrochloride |
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| XIE Zheng-ping,LI Zhong-ming,YOU Qing-liang,YU Zong-yuan.Synthesis and Application of Cetirizine Dihydrochloride[J].Chemistry & Bioengineering,2009,26(1). |
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| Authors: | XIE Zheng-ping LI Zhong-ming YOU Qing-liang YU Zong-yuan |
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| Affiliation: | 1.Hubei Research Institute of Chemistry;Wuhan 430074;China;2.School of Chemistry and Environmental Engineering;Jianghan University;Wuhan 430056;China |
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| Abstract: | Cetirizine dihydrochloride,as the second generation H1-receptor antagonist,is one of the best-selling anti-allergy drugs all over the world.In this paper,the medication safety,efficacy and the latest clinical application of cetirizine dihydrochloride are introduced in brief.Its synthetic routes from four basic materials and their advantages and disadvantages are especially summarized. |
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| Keywords: | cetirizine dihydrochloride synthesis and application anti-allergy action |
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