神经干细胞移植治疗小脑性共济失调的疗效评定 |
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引用本文: | 张建武,郭守刚,汪春娟,孙涛,王泰华. 神经干细胞移植治疗小脑性共济失调的疗效评定[J]. 河南医药信息, 2010, 0(18): 19-20 |
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作者姓名: | 张建武 郭守刚 汪春娟 孙涛 王泰华 |
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作者单位: | [1]山东省红十字会介入医院,济南市250014 [2]山东大学山东省省立医院神经内科,济南市250021 [3]山东医学高等专科学校医学基础系,济南市250012 |
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摘 要: | 目的探讨神经干细胞(Neural stem cells,NSCs)移植对小脑性共济失调的治疗作用。方法对216例小脑性共济失调患者进行NSCs腰椎脊髓蛛网膜下腔注射,分别于治疗前及治疗后180d对患者日常生活自理能力进行评分。结果采用NSCs移植治疗前和治疗后180d的生活自理能力评分分别为(52.25±9.12)、(73.50±11.35),有显著差异(P〈0.05)。结论 NSCs移植治疗能改善小脑性共济失调患者的日常生活自理能力,提高生存质量。
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关 键 词: | 神经干细胞 移植 小脑性共济失调 |
Treadment of Cerebellar Ataxia by Neural Stem Cell Transplantation |
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Affiliation: | ZHANG Jianwu, GUO Shougang, WANG Chunjuan, et al Jieru Hospital of Red Cross of Shandong province, Jinan 250014, China |
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Abstract: | Objective To explore the effects of neural stem cell transplantation in treatment of cerebellar ataxia.Methods To transplant NSCs to a cerebellar ataxia patient by injection through lumbar subarachnoid cavity and to evaluate the score of Barthel index before and 180 days later.Results The scores before and 180 days later are(52.25±9.12)and(73.50±11.35) respectively.There are significantly different.Conclusion NSCs transplantation could contribute to improve the activities of daily living and ameliorate the quality of life for the patients of cerebellar ataxia. |
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Keywords: | Neural stem cell Transplantation Cerebellar ataxia |
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