苯磺酰苯丙氨酸、邻菲咯啉Mg(Ⅱ)配合物的合成、晶体结构及抗菌活性

以MgCl2、苯磺酰苯丙氨酸(BPPA)和邻菲咯啉为原料,合成了一个新型镁配合物Mg(BPPA)2(phen)(H2O)2].(phen).2(H2O)。对其进行了元素分析、红外光谱分析,并用X-射线衍射测定了它的单晶结构。结果表明:配合物属于三斜晶系,P空间群,配合物分子通过分子内和分子间氢键以及π-π堆积作用形成了一维链状结构。初步研究了配体及配合物的抗菌活性,配合物对大肠杆菌、白葡萄球菌及枯草芽孢杆菌有一定的抗菌活性,而配体却没有抗菌活性。

Synthesis, Crystal Structure and Antibacterial Activity of Magnesium(Ⅱ) Complex with N-Benzenesulphonyl-L-phenylalanine and 1,10-Phenanthroline

A new complex bis (N-benzenesulphonyl-L-phenylalanine-O)-bis (water-O)-(1,10-phenanthroline-N,N')-analysis, IR spectroscopy and single-crystal X-ray diffraction. The results showed that the compound was triclinic,with P(-1), a=07.087 0(10) nm, b=1.324 80(15) nm, c=1.621 8(2) nm, α=111.854(2)°,β=101.300(10)° ,γ=95.645(10)°,0.07(11), R=0.048 4, wR=0. 110 8, The complex formed one dimensional chain structure through intramolecule and intermolecule hydrogen bonds and π-π stacking. The antibacterial assay of the magnesium (Ⅱ) complex and the ligand of N-benzenesulphony-L-phenylalanine was tested using a modified version of the 2-fold serial dilution method. The complex shows considerable antibacterial activity against escherichia coli, bacillus subtilis and staphylococcus white, and the ligand did not show antibacterial activity. CCDC: 744536.