CGAP:构建肿瘤研究领域的生物信息技术平台

美国癌症研究所在1996年发起了癌肿基因组解剖计划（CGAP），其目的在于创建一系列工具以获知与肿瘤相炎的基因、蛋白质及其它生物标记物。近年来，生物信息技术的发展为其计划的实施提供了丰富的生物信息资源。常用的生物信息技术有：表达序列标签（EST）、Unigene、基因表达系列分析（SAGE）和数字化差异表达（DDD），四种方法各有其优势，共同成为生物信息技术的组成部分。本文综述了上述生物信息技术在CGAP中的应用，并预测了其未来的发展趋势。

The cancer genome anatomy project: building a bioinformatics index in cancer research fields

National Cancer Institute initiated the project of building the cancer genome anatomy project in order to find a series of indices to retrieve information about genes,proteins and other biological markers related to cancers in 1996.At present,the project has been speeded up with the help of advances in the development of bioinformatics that could provide enormous biological information.Several bioinformations techniques that are commonly used include: Expressed Sequence Tags,Unigene,Serial Analysis of Gene Expression and Digital Differential Display.Each method has its own advantages,which together make up the bioinformatics technology.In this article,we reviewed the application of bioinformatics in cancer research and predict its trend.