2003-2005年山东省医院感染监控网病原菌分布及耐药性监测

目的 了解医院感染病原菌分布及细菌耐药性变迁。方法 统计分析山东省医院感染监控网45所医院2003年1月-2005年12月医院感染资料。结果 病原菌共5 626株,G^-杆菌、G^＋球菌、真菌分别占58.27%、25.84%、15.89%;常见G^-杆菌对氨苄西林的耐药率〉89.00%,72.98%的大肠埃希菌对环丙沙星耐药,金黄色葡萄球菌和凝固酶阴性葡萄球菌对青霉素、氨苄西林和红霉素的耐药率均〉80.00%,前者对克林霉素的耐药率逐年增高至86.64%。结论 医院感染病原菌耐药严重,应加强监测。

Distribution and Resistance of Nosocomial Infection Pathogen from Shandong Provincial Nosocomial Infection Surveillance System 2003-2005

OBJECTIVE To investigate the distribution and bacterial resistance of nosocomial infection.METHODS The data of 45 hospitals from Shandong Provincial Nosocomial Surveillance System from Jan 2003 to Dec 2005 were analyzed.RESULTS Of total 5 626 isolates strains from the nosocomial infection cases,G-bacilli,G+ cocci and fungi accounted for 58.27%,25.84% and 15.89%,respectively.The ampicillin-resistant rate of commonly encountered G-bacilli was above 89%.There were 72.98% of E.coli resistant to ciprofloxacin.The rates of resistance of S.aureus and coagulase negative Staphylococcus to penicillin,ampicillin and erythromycin were all above 80%;the lincomycin-resistant rate of S.aureus increased gradually to 86.64%.CONCLUSIONS Drug resistance of the nosocomial infective bacteria is a serous problem.Surveillance of bacterial resistance should be strengthened.