血液透析联合血液灌流治疗尿毒症皮肤瘙痒疗效观察

目的 探讨血液透析联合血液灌流治疗尿毒症维持性血液透析患者皮肤瘙痒的疗效.方法 选择我院尿毒症并皮肤瘙痒的维持性血液透析患者55例,随机分为血液透析组和血液透析加血液灌流组.血液透析组25例,接受常规透析治疗,每周2～3次.血液透析加血液灌流组30例,在血液透析组治疗的基础上,联合血液灌流,每2周1次.两组共治疗3个月...

Observed the curative effect of treating uremia skin-itch with hemodialysis and hemoperfuison

Objective To explore the curative effect of treating uremia skin-itch with hemodialysis and hemoperfuison.Methods Chose 55 uremia patients taking persistent hemodialysis and having skin-itch; ramdomly divided them into hemodialysis group and hemodialysis combined with hemoperfusion group.25 patients of the hemodialysis group took hemodialysis 2 to 3 times per week.Basing on the treatment of the hemodialysis group,the hemodialysis combined with hemoperfusion group took hemoperfusion every other week.Both groups were treated for 3 months.Observed all patients' skin-itch meliortion.Tested the change of parathyroid hormone,β 2 microglobulin,P,and Ca2+ in blood.Results The patients of hemodialysis combined with hemoperfusion group had lower parathyroid hormone[( 314.5± 182.4) ng/L vs.479.2 ± 207.1ng/L],β 2microglobulin[( 16.1 ± 7.3) mg/Lvs.(24.2 ± 11.2) mg/L],and P3- [( 2.03 ± 0.91 )mmol/L vs.( 2.81 ± 1.42 )mmol/L )]in blood than the patients of hemodialysis group ( P ＜ 0.05 ) and that before treatment ( P ＜ 0.05 ),and got some obvious improvement on skin-itch ( 24/30 ).No patients in hemodialysis group got obvious improvement on skin-itch.Blood parathyroid hormone,β 2 microglobulin,and p3- had no obvious change in the patients of hemodialysis group( P＞0.05 ).Patients' blood Ca2+ in both groups had no obvious change( P＞ 0.05 ).Conclusion Hemodialysis combined with hemoperfusion is an effective treatment method for the uremia patients taking persistent dialysis and having skin-itch.