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| 探讨LC-MS技术在快速发现和鉴定药物有关物质及代谢产物中的应用 | |
| 引用本文： | 王雷娜,景士云,宋敏,杭太俊,姜红,文红梅,张正行.探讨LC-MS技术在快速发现和鉴定药物有关物质及代谢产物中的应用[J].药学进展,2007,31(8):358-363. |
| 作者姓名： | 王雷娜 景士云 宋敏 杭太俊 姜红 文红梅 张正行 |
| 作者单位： | 1. 中国药科大学药物分析教研室,江苏,南京,210009 2. 哈药集团制药总厂,黑龙江,哈尔滨,150046 3. 南京中医药大学中医药研究院,江苏,南京,210029 |
| 摘 要： | 探讨LC-MS技术在快速发现和鉴定药物的微量有关物质及代谢产物中的应用,简述LC-MS技术应用原理,介绍LC-MS技术用于药物有关物质和代谢产物快速发现与鉴定的典型实例。 |
| 关 键 词： | LC-MS技术 药物有关物质 代谢产物 发现 鉴定 |
| 文章编号： | 1001-5094（2007）08-0358-06 |
| 收稿时间： | 2007-05-10 |
| 修稿时间： | 2007年5月10日 |
A Discussion on Quick Discovery and Identification of Drug-related Substances and Metabolites by LC-MS Method |
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| WANG Lei-na,JING Shi-yun,SONG Min,HANG Tai-jun,JIANG Hong,WEN Hong-mei,ZHANG Zheng-xing.A Discussion on Quick Discovery and Identification of Drug-related Substances and Metabolites by LC-MS Method[J].Progress in Pharmaceutical Sciences,2007,31(8):358-363. | |
| Authors: | WANG Lei-na JING Shi-yun SONG Min HANG Tai-jun JIANG Hong WEN Hong-mei ZHANG Zheng-xing |
| Affiliation: | 1. Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing 210009, China; 2. General Pharmaceutical Factory, Harbin Pharmaceutical Group, Harbin 150046, China; 3. Institute of Traditional Chinese Medicine, Nanjing University of Traditional Chinese Medicine, Nanfing 210029, China |
| Abstract: | The application of LC-MS method in the quick discovery and identification of trace drug-related substances and metabolites was discussed. The application principle was elucidated briefly. The typical examples in the application were introduced. |
| Keywords: | LC-MS method Drug-related substance Metabolite Discovery Identification |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
