106例抗菌药物的不良反应分析

目的 探讨我院2009年抗菌药物的不良反应发生特点及规律，为临床安全用药提供参考。方法：采用回顾性研究方法，对我院2009年收集的106例抗菌药物的不良反应进行分析。结果：抗菌药物的不良反应在我院上报不良反应中居首位，其中导致不良反应的主要抗菌药物为头孢菌素类、大环内酯类、喹诺酮类药物。结论：应重视抗菌药物的不良反应，加强对抗菌药物的不良反应监测，促进合理使用抗菌药物。

Analysis of 106 Cases of Adverse Drug Reactions Induced by Antibacterials

Objective To study the occurrence and distribution of adverse drug reactions（ADR） induced by antibacterials in our hospital to provide reference to clinical rational drug use of antibacterial agents. Methods 106 reports of ADR cases induced by antibacterials from 2009 in our hospital clinical departments were collected and analyzed ret- rospectively by drug types, drug names, route of administration and clinical manifestations. Results Antibacterials had occupied the first place in our hospital＇s adverse drug reaction, most of them resulted from cephalosporins, macrolides and quinolones. Conclusion It is necessary to pay more attention the ADR induced by antibacterials to promote the rational use of antibacterials.