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毒死蜱的神经毒性作用及机制
引用本文:王会平,伍一军.毒死蜱的神经毒性作用及机制[J].劳动医学,2008,25(3):314-318.
作者姓名:王会平  伍一军
作者单位:中国科学院动物学研究所分子毒理学实验室农业虫害鼠害综合治理研究国家重点实验室
基金项目:国家高技术研究发展计划(863计划),国家科技支撑计划
摘    要:毒死蜱是目前世界上生产和销售量最大的有机磷杀虫剂之一,广泛应用于农作物病虫害和家庭卫生害虫防治之中,其对环境中生物的毒性尤其是对人类健康的影响一直是毒理学研究热点。本综述就毒死蜱的最主要毒性——神经毒性及其毒性作用机制的研究进展作一详细报道。

关 键 词:毒死蜱  神经毒性  作用机制

Neurotoxicity and Mechanisms of Chlorpyrifos
WANG Hui-ping,WU Yi-jun.Neurotoxicity and Mechanisms of Chlorpyrifos[J].Journal of Labour Medicine,2008,25(3):314-318.
Authors:WANG Hui-ping  WU Yi-jun
Affiliation:WANG Hui-ping, WU Yi-jun( 1.Laboratory of Molecular Toxicology, State Key Laboratory for Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; 2.Graduate School of Chinese Academy of Sciences, Beijing 100039, China )
Abstract:Chlorpyrifos,one of the organophosphorus insecticides holding the most production and sales volumes in the world,has been widely used in the prevention and control of crop diseases and pests.The toxicity of chlorpyrifos and its mechanisms are being studied by more and more toxicologists.The present article is a review on the neurotoxicity,the most important toxicity induced by chlorpyrifos and the recent progress with the researches on mechanisms of its toxicity.
Keywords:chlorpyrifos  neurotoxicity  mechanism
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