阿奇霉素序贯疗法治疗小儿支原体肺炎疗效观察

目的探讨阿奇霉素序贯疗法对小儿支原体肺炎的治疗效果。方法将98例小儿支原体肺炎患者按照入院时间先后顺序随机分为两组，每组49例，分别标记为对照组、实验组。对照组患者给予阿奇霉素静脉连续滴注，实验组患者采用阿奇霉素静脉注射，连续5d后转为阿奇霉素口服治疗，比较两组患者治疗效果。结果实验组患者治疗有效率为91．83％，对照组治疗有效率为59．18％，两组比较差异具有统计学意义（P〈0．05）。实验组患者8例患者发生不良反应，发生率为16．32％，对照组患者24例患者发生不良反应，发生率为48．97％，两组患者比较差异具有统计学意义（P〈0．05）。结论阿奇霉素序贯疗法治疗小儿支原体肺炎临床疗效确切，不良反应较少，值得临床推广应用。

Mycoplasma pneumoniae efficacy of azithromycin sequential therapy

Objective To investigate the effect of azithromycin sequential therapy in children with mycoplasma pneumonia. Methods The 98 cases of mycoplasma pneumonia patients admitted to hospital in chronological order according to randomized into two groups, 49 cases were labeled as the control group, the experimental group. In the control group were treated with azithromyein intravenous continuous infusion, the experimental group were treated with intravenous azithromycin, 5 days in a row into oral azithromycin treatment, treatment groups were compared. Results Effective treatment of patients in the experimental group was 91.83%, the control group was 59.18% effective, the difference was statistically significant （P〈0.05）. 8 patients in the experimental group patients had side effects, the rate was 16.32%, 24 patients in the control group of patients the occurrence of side reactions, the rate was 48.97%, comparing the two groups were statistically significant differences （P〈0.05）. Conclusion Azithromycin sequential therapy mycoplasma pneumoniae clinical efficacy, fewer side effects, worthy of clinical application.