A new benzofuran derivative from Nicotiana tabacum |
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Authors: | Jian-Jun Xia Yuan-Dong Li Xiu-Ming Liu Yuan Lu Yi-Qin Wu |
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Affiliation: | Technology Center, China Tobacco Yunnan Industrial Co., Ltd, Kunming 650202, China |
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Abstract: | A new benzofuran derivative, methyl 3-acetyl-7-hydroxy-6-methoxy-2-methylbenzofuran-4-carboxylate (1), and a known compound pyrrolezanthine (2), were isolated from leaves of Nicotiana tabacum. Compound 1 was elucidated by means of spectroscopic methods, as well as X-ray diffraction. Both compounds 1 and 2 exhibited moderate inhibitory activities on human cancer cell lines. |
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Keywords: | Nicotiana tabacum benzofuran cytotoxicity |
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