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A new benzofuran derivative from Nicotiana tabacum
Authors:Jian-Jun Xia  Yuan-Dong Li  Xiu-Ming Liu  Yuan Lu  Yi-Qin Wu
Affiliation:Technology Center, China Tobacco Yunnan Industrial Co., Ltd, Kunming 650202, China
Abstract:A new benzofuran derivative, methyl 3-acetyl-7-hydroxy-6-methoxy-2-methylbenzofuran-4-carboxylate (1), and a known compound pyrrolezanthine (2), were isolated from leaves of Nicotiana tabacum. Compound 1 was elucidated by means of spectroscopic methods, as well as X-ray diffraction. Both compounds 1 and 2 exhibited moderate inhibitory activities on human cancer cell lines.
Keywords:Nicotiana tabacum  benzofuran  cytotoxicity
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