Impact of automatic orders to discontinue vancomycin therapy on vancomycin use in an antimicrobial stewardship program. |
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Authors: | Denise M Connor Shawn Binkley Neil O Fishman Leanne B Gasink Darren Linkin Ebbing Lautenbach |
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Affiliation: | Division of Infectious Diseases, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA. |
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Abstract: | We examined the possible unintended consequences of a 72-hour automatic order to discontinue vancomycin therapy in an antimicrobial stewardship program (ASP). Of 120 patients, 11 had vancomycin therapy discontinued at 72 hours without a call to the ASP, and 7 experienced a treatment interruption of 6-36 hours. All discontinuation of therapy was considered appropriate, and the 7 treatment interruptions did not have clear clinical consequences. Only one-third of patients had ASP stickers that warned of impending discontinuation of vancomycin therapy placed appropriately in the medical record. |
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