非洛地平，氨氯地平对高血压病患者24小时血压的影响

目的比较非洛地平，氨氯地平对高血压病患者24小时血压的降压疗效。 方法采用随机、单盲和平行对照的方法，运用24小时动态血压监测。 结果二药均能显著降低血压，彼此间降低偶测血压的幅度无显著差异。二药均能降低24小时平均，白天平均及夜间平均血压，均能有效控制清晨血压高峰期的血压。 结论　非洛地平，氨氯地平均可每日服用1次，均能有效控制24小时血压及清晨醒后的高峰期血压。

The Efficacy of Filodipine and Amlodipine on 24 h Blood Pressure in Pat ients with Essentia1 Hypertension

Objective　To Compare the anti hypertensive effects of felodipine and amlodipine on 24 hours blood pressure in patients with essential hypertensin. Method A Radomized， single blind and contro11ed study was perfo rmed and blood pressuree was measured by 24 hours ambulatory blood pressure monitoring. Results Felodipine and amlodipine signiflcantly reduced both s ysto1ic and diasto1ic casual b1ood preessure when compared with placebo and no differences were observed between the two drugs． Felodipine and amlodipine reduce 24h mean，daytime mean ambulatory blood pressure．The rapid rise in blood pressure i n the morning hours was well contro11ed by the two drugs. Conclusion:Felodipine and amlodipine used once daily could cont rol 24 h blood pressure effectively in patients of essential hypertension．