开腹腹部手术延迟性术后肠麻痹的危险因素分析

目的 旨在研究首都医科大学附属北京友谊医院腹部手术后延迟性肠麻痹（prolonged postoperative ileus，PPOI）危险因素。方法 纳入2016年7月至2017年12月间于首都医科大学附属北京友谊医院普外科接受开腹消化道肿瘤根治术的患者123例为研究对象。以出现PPOI为病例组（13例），其余为对照组（110例）。采用单因素和多因素Logistic回归模型分析PPOI的危险因素。结果 单因素分析显示体质量指数（body mass index，BMI）（χ²=6.824，P=0.009）、术后出现低钾血症（χ²=3.872，P=0.049）与PPOI发生相关。多因素Logistic回归分析结果示BMI<18.5 kg/m²是PPOI发生的独立危险因素。结论 BMI是PPOI的独立危险因素，当BMI<18.5 kg/m²，发生术后延迟性肠麻痹的危险性增加。

Analysis of risk factors for prolonged postoperative ileus in patients undergoing major abdominal surgery

Objective To determine the incidence and risk factors of prolonged postoperative ileus (PPOI) after major abdominal surgery in our hospital. Methods From July 2016 to December 2017, 123 patients who underwent radical operation of open digestive tract tumor were enrolled in the general surgery department of Beijing Friendship Hospital, Capital Medical University. Patients with PPOI were set as the case group (13 cases), otherwise it was the control group (110 cases). Univariate and multivariate logistic regression models were used to analyze the risk factors of PPOI. Results Univariate analysis showed that body mass index (BMI) <18.5 kg/m² (χ²=6.824, P=0.009) and postoperative hypokalemia (χ²=3.872, P=0.049) were related to PPOI. Multivariate regression analysis showed that BMI <18.5 kg/m² was an independent risk factor for PPOI. Conclusion The risk factors of PPOI may include BMI <18.5 kg/m² and postoperative hypokalemia. According to the chi-square test and logistic regression analysis, BMI is an independent risk factor for PPOI. The patients will be more at risk of PPOI when BMI<18.5 kg/m².