手外科专科医院感染病原菌分布及耐药性分析

目的分析江苏省无锡市第九人民医院2011年临床分离出的细菌构成及耐药性情况。方法回顾性分析医院2011年临床标本培养分离出的病原菌的分布、构成和耐药性。结果 2011年临床标本培养分离出533株病原菌,分离率位于前5位的病原菌是:金黄色葡萄球菌(25.69%),大肠埃希菌(15.20%),铜绿假单胞菌(14.63%);鲍曼不动杆菌(10.69%)和肺炎克雷伯菌(9.94%)。金黄色葡萄球菌对万古霉素、利奈唑胺敏感性较好,但对其他常用抗菌药敏感性不佳;肠杆菌科对亚胺培南和哌拉西林/他唑巴坦敏感性较好,对其他药物敏感性不佳;假单胞菌属对常用药物的敏感性高于不动杆菌属,它们对哌拉西林/他唑巴坦敏感性较好。结论手外科专科医院分离病原菌对常用药的耐药率较高,临床医师应熟悉常见分离菌的耐药情况,根据抗菌药物敏感性试验,合理选用抗菌药物,减少耐药菌株的产生。

Distribution of pathogenic bacteria and resistance to antibiotics in specialist hospital

Objective To analyze the distribution of pathogenic bacteria and resistance to antibiotics in Wuxi No.1 9 People′s Hospital in 2011.Methods The distribution and the antimicrobial susceptibility of pathogens,which were isolated from the clinical specimens in 2011,were analyzed retrospectively.Results A total of 533 strains of pathogens were isolated.The five common bacteria were staphylococcus aureus(25.69%),escherichia coli(15.20%),pseudomonas aeruginosa(14.63%),acinetobacter baumanii(10.69%) and klebsiella pneumoniae(9.94%).Staphylococcus aureus were more sensitive to vancomycin and linezolid than to other antibiotics.Enterobacteriaceae were more sensitive to imipenem and piperacillin-tazobactam than to other antibacterial.Pseudomonas were more sensitive to antibacteria than acinetobacter,but they were sensitive to piperacillin-tazobactam.Conclusion The bacteria isolated from specialist hospital is resistant to most of antibiotics.Clinicians should be familiar with the change of drug-resistant bacteria and conduct the rational use of antibiotics according to drug susceptibility test.