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脊柱骨巨细胞瘤及其外科治疗
引用本文:朱海波,包聚良,倪斌,袁文,陈爱民,肖建如. 脊柱骨巨细胞瘤及其外科治疗[J]. 第二军医大学学报, 2000, 21(7): 660-663
作者姓名:朱海波  包聚良  倪斌  袁文  陈爱民  肖建如
作者单位:第二军医大学长征医院骨科,上海,200003
摘    要:目的:研究脊柱骨巨细胞瘤的影像学特点,探讨手术方式及其预后的影响。方法:56例均行手术治疗,早期实施单纯肿瘤病灶切除术,后期施行肿瘤整块切除术和病椎次全切除术,同时给予坚强的内固定。结果:术后所有患者局部疼痛均有不同程度的缓解,77.3%的患者神经体征得到改善。随访42例(平均随访5年4个月)中预后良好无复发者25例(59.5%),局部仍有瘤灶存在但病变不超过术前者11例(26.2%),病变扩大,

关 键 词:脊柱骨巨细胞瘤 外科手术 术式 预后

Giant cell tumor of the spine and its surgical treatment
ZHU Hai-Bo,BAO Ju-Liang,NI Bin,YUAN Wen,CHEN Ai-Min,XIAO Jian-Ru. Giant cell tumor of the spine and its surgical treatment[J]. Former Academic Journal of Second Military Medical University, 2000, 21(7): 660-663
Authors:ZHU Hai-Bo  BAO Ju-Liang  NI Bin  YUAN Wen  CHEN Ai-Min  XIAO Jian-Ru
Abstract:Objective: To study the radiographic manifestation on the giant cell tumor on the spine and to discuss the relationship between operation and prognosis. Methods: Operation were performed on 56 cases. Some were simple curettage of tumor lesion in the early stage, some were total resections of tumor or semi spondylectomy accompanied by strong inter fixation. Results: Pain were relieved in all cases postoperatively and the neurological defects were improved in 77.3% of all cases. Forty two cases were followed up and 25 cases (59.5%) had excellent healing with no recurrence. The tumor lesion still existed in 11 cases (26.2%, which did not exceed the lesion field before operation), 6 cases (14.3% ) worsened. Conclusion: The giant cell tumor of spine has its own specific radiographic feature. There is some recurrence in simple curettage of tumor lesion. The thoroughly en bloc resection of tumor or spondylectomy, bone fusion and strong inter fixation are the key points for successful surgical treatment, the clinic behavior of bone giant cell tumor is somewhat unpredictable.
Keywords:spine  giant cell tumors  surgery   operative
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