| 响应面法优化超声提取波罗蜜叶中总黄酮的工艺 |
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| 引用本文： | Wang HW,Liu YQ,Wang YH. 响应面法优化超声提取波罗蜜叶中总黄酮的工艺[J]. 中药材, 2011, 34(7): 1125-1129 |
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| 作者姓名： | Wang HW Liu YQ Wang YH |
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| 作者单位： | 肇庆学院化学化工学院;肇庆市结核病防治所; |
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| 基金项目： | 广东省科技计划项目(粤科函社字[2010]1096号) |
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| 摘 要： | 目的:以乙醇为提取剂,用超声辅助法从波罗蜜叶中提取总黄酮。方法:通过单因素试验分别考察乙醇体积分数、浸提时间和液料比对波罗蜜黄酮提取量的影响,确定各因素的适宜水平。在此基础上,利用Design-Ex-pert软件Box-Behnken中心组合设计法设计响应面分析乙醇体积分数、超声时间和液料比3个因素对总黄酮提取率的影响,并通过方差分析回归建立数学模型。结果:波罗蜜叶黄酮超声提取的最佳工艺为:乙醇体积分数为69.4%,超声32 min,液料比为22.6∶1 mL/g,在此条件下,黄酮提取量达到7.55 mg/g。结论:Box-Behnken设计结合响应面分析法可以很好地对波罗蜜叶总黄酮超声提取工艺进行优化。
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| 关 键 词： | 波罗蜜 黄酮 响应面分析 工艺优化 |
Optimization of ultrasonic-assisted extraction of total flavonoids from leaves of the Artocarpus heterophyllus by response surface methodology |
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| Wang Hong-wu,Liu Yan-qing,Wang Yuan-hong. Optimization of ultrasonic-assisted extraction of total flavonoids from leaves of the Artocarpus heterophyllus by response surface methodology[J]. Journal of Chinese medicinal materials, 2011, 34(7): 1125-1129 |
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| Authors: | Wang Hong-wu Liu Yan-qing Wang Yuan-hong |
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| Affiliation: | WANG Hong-wu1,LIU Yan-qing1,WANG Yuan-hong2(1.School of Chemistry & Chemical Engineering,Zhaoqing University,Zhaoqing 526061,China,2.Zhaoqing Municipal Institute of Tuberculosis,Zhaoqing 526020,China) |
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| Abstract: | Objective:To investigate the ultrasonic-assisted extract on of total flavonoids from leaves of the Artocarpus heterophyllus.Methods:Investigated the effects of ethanol concentration,extraction time,and liquid-solid ratio on flavonoids yield.A 17-run response surface design involving three factors at three levels was generated by the Design-Expert software and experimental data obtained were subjected to quadratic regression analysis to create a mathematical model describing flavonoids extraction.Results:The... |
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| Keywords: | Artocarpus heterophyllus Lam. Flavonoids Response surface methodology Ultrasonic assisted extraction |
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