宫颈癌患者宫颈粘液CEA测定的临床意义

应用放射免疫技术对50例宫颈癌患者及24例非恶性肿瘤患者的宫颈粘液及外周血CEA的含量进行了测定，结果：宫颈癌患者宫颈粘液CEA测定值及阳性率明显高于对照组（P＜0．05，P＜0．01）。良、恶性病变的宫颈粘液CEA均明显高于外周血中CEA含量（P＜0.01，P＜0．02）。而宫颈癌患者血CEA测定值及阳性率与对照组比较均无差异（P＞0．05）。宫颈癌患者治疗前、后宫颈粘液CEA测定值差异有显著性（P＜0.01）。作者认为：宫颈粘液CEA的测定对宫颈癌的诊断及疗效评价较血CEA的测定更有意义。

Clinical Significance of Cervical Mucus CEA Assay in Patients with Carcinoma of the Cervix

The CEA coto of cervical mucus patients and periphend serum was detendned in 50 cerricalareinoma patients and 24 nonmalignant tumor patients by a radioimmunoassay technique, The CEA levelsand positive rate of cervical mucus in cewical carcinoma group were significantly higher than that incontrol group (P <0.05 ana P < 0.01 respectively) .The levels of cervical mucus CEA in benigh andmalignant Patients were significantly higher than those of peripheral serum CEA(P < 0.01 and P <0.02,respectively). There was no significant no in serum CEA leve and positive rate betweencervical cance group and control group(P > 0.05). There was a significant dence about cervicalmucus CEA in cervical carcinoma Patients before and after treatment (P <0. 01 ). The writers of thisarticle think tha the CEA level of cervical mucus is a more useful index than that of the serum indiagnozing and evalusting the curative effect of cervical cancer.