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Radiation hybrid map construction problem parameterized
Authors:Chihao Zhang  Haitao Jiang  Binhai Zhu
Affiliation:1. Department of Computer Science, Shanghai Jiao Tong University, Shanghai, 200240, China
2. School of Computer Science and Technology, Shandong University, Jinan, 250100, Shandong, China
3. Department of Computer Science, Montana State University, Bozeman, MT, 59717-3880, USA
Abstract:In this paper, we study the Radiation hybrid map construction ( $\mathsf{{RHMC} }$ ) problem which is about reconstructing a genome from a set of gene clusters. The problem is known to be $\mathsf{{NP} }$ -complete even when all gene clusters are of size two and the corresponding problem ( $\mathsf{{RHMC}_2 }$ ) admits efficient constant-factor approximation algorithms. In this paper, for the first time, we consider the more general case when the gene clusters can have size either two or three ( $\mathsf{{RHMC}_3 }$ ). Let ${p\text{- }\mathsf {RHMC} }$ be a parameterized version of $\mathsf{{RHMC} }$ where the parameter is the size of solution. We present a linear kernel for ${p\text{- }\mathsf {RHMC}_3 }$ of size $22k$ that when combined with a bounded search-tree algorithm, gives an FPT algorithm running in $O(6^kk+n)$ time. For ${p\text{- }\mathsf {RHMC}_3 }$ we present a bounded search tree algorithm which runs in $O^*(2.45^k)$ time, greatly improving the previous bound using weak kernels.
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