Salmonella of Indian origin: pseudo-susceptibility to fluoroquinolones |
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Authors: | Denes E Gondran G Bezanahary H Genet C Rogez J P Weinbreck P Martin C |
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Affiliation: | Service des maladies infectieuses et tropicales, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France. eric.denes@unilim.fr |
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Abstract: | We report the case of a patient presenting with typhoid fever after returning from a stay in India. This infection was not cured with a course of ciprofloxacin, due to a reduced susceptibility of the bacteria to the drug. This decreased susceptibility to fluoroquinolones was not detected by the antibiogram, but the MIC for nalidixic acid was greater than 32 mg/l. This case suggests using a third generation cephalosporin instead of a quinolone, for people coming from a high-risk zone. It also suggests that the MIC for nalidixic acid and for norfloxacin can be used as the first clue for a reduced susceptibility to fluoroquinolones. |
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