The impact of positron emission tomography/computed tomography in edge delineation of gross tumor volume for head and neck cancers |
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| Authors: | Ashamalla Hani Guirgius Adel Bieniek Ewa Rafla Sameer Evola Alex Goswami Ganesh Oldroyd Randall Mokhtar Bahaa Parikh Kapila |
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| Affiliation: | Department of Radiation Oncology, New York Methodist Hospital, Weill Medical College of Cornell University, New York, NY, USA. hashamalla@aol.com |
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| Abstract: | PURPOSE: To study anatomic biologic contouring (ABC), using a previously described distinct halo, to unify volume contouring methods in treatment planning for head and neck cancers. METHODS AND MATERIALS: Twenty-five patients with head and neck cancer at various sites were planned for radiation therapy using positron emission tomography/computed tomography (PET/CT). The ABC halo was used in all PET/CT scans to contour the gross tumor volume (GTV) edge. The CT-based GTV (GTV-CT) and PET/CT-based GTV (GTV-ABC) were contoured by two independent radiation oncologists. RESULTS: The ABC halo was observed in all patients studied. The halo had a standard unit value of 2.19 +/- 0.28. The mean halo thickness was 2.02 +/- 0.21 mm. Significant volume modification (>or=25%) was seen in 17 of 25 patients (68%) after implementation of GTV-ABC. Concordance among observers was increased with the use of the halo as a guide for GTV determination: 6 patients (24%) had a
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| Keywords: | PET/CT planning Head-and-neck cancers GTV contouring Anatomic biologic halo |
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