空腹血糖升高的老年男性人群十年死亡率分析

目的 分析不同空腹血糖(FPG)水平的老年男性人群十年全因死亡率特别是心脑血管疾病死亡率的情况.方法 老年男性人群共1 572人, 按照基线FPG水平分为4组[FPG(mmol/L)＜ 5.6,5.6≤FPG＜6.1,6.1≤FPG＜7.0,FPG≥7.0]进行十年死亡率的分析.累积生存率的估计采用Kaplan-Meier 方法,生存率的比较采用log-rank检验.Logistic回归模型用于死亡率经各种危险因素调整的相对危险度(RR)表示以及与全因死亡及心脑血管死亡相关因素的分析.结果 各组十年全因死亡率[(12.6,19.5, 20.5, 27.9)/千人年]及心脑血管死亡率[(2.8, 7.7, 8.6, 14.0)/千人年]差异均有显著性(均P＜0.05),Logistic回归模型结果显示与老年人群全因死亡率有关的因素仅为年龄,而与心脑血管疾病死亡率密切相关的因素为年龄、体重指数、FPG以及心脑血管疾病病史.结论 在老年男性人群中心脑血管疾病是主要死亡原因之一,随着FPG水平的升高,老年男性人群全因死亡率及心脑血管疾病死亡率有所升高.

Analysis of ten-year mortality in the male senile population with elevated fasting plasma glucose

Objective To observe the all-cause and cardiocerebrovascular disease(CCVD)-related mortalities in the senile male population and the relationship of them with fasting plasma glucose (FPG) level.Methods A survey was performed among 1 572 male subjects aged 60-90.All the subjects were groups were calculated by Kaplan-Meier method and the log-rank test was used to compare the survival rates of the 4 groups.Logistic regression model was used to analyze the correlation factors of all-cause mortality and CCVD-related regression model analysis showed that age was related with the all-cause mortality.Among all these factors, age, body mass index, FPG and the history of CCVD had the relationships with the mortality of CCVD.Conclusion In the older male population, CCVD are considered as one of the main causes of death.With the increased levels of FPG, the all-cause mortality and CCVD mortality of senile male population are increased.