纵隔原发性恶性生殖细胞瘤的CT和MRI表现

目的：探讨纵隔原发性恶性生殖细胞瘤的CT和MRI影像表现特点,以提高对本病的认识和诊断水平.方法：经病理证实的纵隔原发性恶性生殖细胞瘤13例,总结和分析其临床、CT及MRI表现.观察项目包括病灶数目、部位、大小,内部结构、边界及与周围结构的关系等.结果：13例均为青壮年患者,单发病灶,位于前中上纵隔,病灶最大截面直径约63 mm.CT表现为病灶内密度不均匀,可见片状坏死,增强后呈明显不均匀轻度强化.4例行MRI扫描,T1WI示病灶呈等信号或稍低信号、T2WI呈等信号或稍高信号,肿瘤内信号不均匀,12例伴有出血、坏死灶,增强扫描呈不均匀轻度～中度强化.病灶边界欠清,其中11例病变与纵隔血管间脂肪间隙消失,10例可见病变周围结构受侵犯,9例血管受侵,3例合并上腔静脉闭塞,6例累及心包,3例侵犯前胸壁及胸骨.结论：纵隔原发性恶性生殖细胞瘤CT和MRI表现具有恶性肿瘤侵袭性的特征,但影像表现缺乏特异性;结合临床及实验室检查有助于恶性生殖细胞瘤的诊断.

CT and MRI features of mediastinal primary malignant germ cell tumor

Objective:To investigate the CT and MRI manifestations of primary mediastinal malignant germ cell tumor in order to improve the knowledge and diagnostic accuracy of the disease.Methods:The clinical materials and CT/MRI manifestations of 13 patients with pathology proven primary malignant germ cell tumor in mediastinum were retrospectively analyzed.The number,location,size,intra-tumoral structures,margin of the tumor and the relationship of tumor with adjacent organs and tissues were studied.Results:All of t...