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| 箬叶多糖对宫颈癌的抑制及免疫功能的影响 | |
| 引用本文： | 靳祎,王恩军,宋洁,关宏,刘斌. 箬叶多糖对宫颈癌的抑制及免疫功能的影响[J]. 中国计划生育学杂志, 2012, 20(3): 164-167 |
| 作者姓名： | 靳祎 王恩军 宋洁 关宏 刘斌 |
| 作者单位： | 1. 河北大学医学部基础医学院,保定,071000 2. 河北省保定市第一中心医院 3. 河北省保定市急救中心 |
| 基金项目： | 河北省人口和计划生育委员会科研计划项目,河北省中医药管理局科研计划项目,保定市科技局科学技术研究与发展指导计划项目 |
| 摘 要： | 目的:探讨箬叶多糖对荷瘤小鼠的抗肿瘤作用及免疫学功能的影响。方法:采用小鼠宫颈癌U14细胞移植瘤模型,观察3个剂量箬叶多糖的体内抗肿瘤作用,并测定荷瘤小鼠脾指数、T淋巴细胞的增殖刺激指数、腹腔巨噬细胞的吞噬指数。结果:箬叶多糖3个剂量组对荷瘤小鼠肿瘤的生长都有一定的抑制作用,并能增加小鼠脾指数,促进淋巴细胞转化,提高荷瘤小鼠腹腔巨噬细胞的吞噬百分率和吞噬指数。结论:箬叶多糖在小鼠体内可以抑制肿瘤的生长,并能增强机体免疫功能。 |
| 关 键 词： | 箬叶 多糖 宫颈癌 免疫功能 U14 细胞 |
Impact of indocalamus tesselatus polysaccharides on cervical cancer and immunity |
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| Jin Yi , Wang Enjun , Song Jie , Guan Hong , Liu Bin. Impact of indocalamus tesselatus polysaccharides on cervical cancer and immunity[J]. Chinese Journal of Family Planning, 2012, 20(3): 164-167 | |
| Authors: | Jin Yi Wang Enjun Song Jie Guan Hong Liu Bin |
| Affiliation: | 1.School of Basic medical Sciences,Hebei University,Hebei 071000;2.Emergency Department,First Center Hospital;3.Medical Department,Baoding Medical Emergency Center |
| Abstract: | Objective:To explore the inhibition of indocalamus tessellatus polysaccharides on tumor growth and its immune regulation.Methods:U14-bearing-mice were used to observe the inhibitory action of indocalamus tessellatus polysaccharides on tumor growth and determine the index of spleen,the proliferation index of T lymphocyte and the phagocytic index of peritoneal macrophage.Results:Three doses of Indocalamus tessellatus polysaccharides showed tumor-inhibitory effects,increased the index of spleen,promoted lymphocyte transformation and increased phagocytic percentage as well as index of peritoneal macrophage.Conclusion:Indocalamus tessellatus polysaccharides can inhibit tumor growth and enhance immune regulation in vivo. |
| Keywords: | Indocalamus tessellatus polysaccharides Cervical cancer Immune function U14 cell |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |
