| 间接免疫荧光法检测婴幼儿急性下呼吸道合胞病毒感染的特异性IgM |
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| 引用本文： | 严淑芳,易著文,高洁生,曾东源,杨艳辉,周汉昭,熊正东,陈英杰.间接免疫荧光法检测婴幼儿急性下呼吸道合胞病毒感染的特异性IgM[J].中南大学学报(医学版),1986(3). |
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| 作者姓名： | 严淑芳 易著文 高洁生 曾东源 杨艳辉 周汉昭 熊正东 陈英杰 |
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| 作者单位： | 湖南医学院第二附属医院儿科病毒室
(严淑芳，易著文，高洁生，曾东源，杨艳辉)，湖南医学院第二附属医院儿科教研室
(周汉昭，熊正东)，湖南医学院第二附属医院儿科教研室(陈英杰) |
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| 摘 要： | 本文对1984年1～3月和1985年3～8月共107例急性下呼吸道感染的住院患儿,采用间接免疫荧光法检测其急性期血清抗RSV特异性IgM抗体,并与病毒分离和/或中和试验比较,敏感性为82.1％,特异性为71.8％。RSV感染患儿发病后3天内大多数病例即可从血清中检测出RSV-IgM,因此该法具有早期诊断价值。
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| 关 键 词： | 免疫球蛋白类 μ链 呼吸道合胞病毒 荧光抗体技术 婴儿 儿童 学龄前 诊断 |
A STUDY FOR DETECTION OF SPECIFIC IgM ANTIBODY AGAINST RSV IN INFANTS AND YOUNG CHILDREN BY IIFA |
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| Yan Shufang Yi Zhuwen Gao Jisesheng Zeng Dongyuan Yang YanhuiVirological Laboratory of Pediatrics,The Second Affiliated Hospital,Hunan Medical CollegeZhou Hanzhao Xiong Zhengdong Chen Yingjie.A STUDY FOR DETECTION OF SPECIFIC IgM ANTIBODY AGAINST RSV IN INFANTS AND YOUNG CHILDREN BY IIFA[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1986(3). |
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| Authors: | Yan Shufang Yi Zhuwen Gao Jisesheng Zeng Dongyuan Yang YanhuiVirological Laboratory of Pediatrics The Second Affiliated Hospital Hunan Medical CollegeZhou Hanzhao Xiong Zhengdong Chen Yingjie |
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| Affiliation: | Yan Shufang Yi Zhuwen Gao Jisesheng Zeng Dongyuan Yang YanhuiVirological Laboratory of Pediatrics,The Second Affiliated Hospital,Hunan Medical CollegeZhou Hanzhao Xiong Zhengdong Chen YingjieDepartment of Pediatrics,The Second Affiliated Hospital,Hunan Medical College |
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| Abstract: | RSV-IgM has been detected with IIFA in 107 cases of ALRTI infants and younger children. As compared with virus isolation and/or neutralization test, the sensitivity of IIPA was 82.1%, the specificity 71.8%. RSV-IgM of cases was detected within the first 3 days. It is suggested that the detection of RSV-IgM of ALRTI is satisfactory method for early diagnosis of RSV infection. |
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| Keywords: | Immunoglobulins Mu chain Respiratory syncytial virus Fluorescent antibody technic Infant Child preschool Diagnosis |
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