调整血脂对冠心病预后的影响

目的：探讨长期调脂治疗对冠心病患者预后的影响。方法：对８６例伴有高脂血症的冠心病患者进行（３．１±０．７）年的调脂治疗（观察组），并以同期未进行调脂治疗的１１３例为对照（对照组）。结果：与治疗前相比，治疗后观察组血ＴＣ、ＴＧ、ＬＤＬ－Ｃ、ＡｐｏＢ１００明显下降，ＨＤＬ－Ｃ、ＡｐｏＡ１明显增高（Ｐ＜０．０１）。随诊观察表明，心脏事件的发生率观察组为２７．９１％，并随观察时间的延长而逐渐下降（Ｐ＜０．０５），对照组为８７．６１％，且随观察时间的延长而逐渐增高（Ｐ＜０．０１）。结论：长期的调脂治疗对冠心病患者的预后具有明显的改善作用。

Effect of Lipid-adjusting Therapy on the Prognosis of Coronary Heart Disease

Objectives: It was amied to investigate the effect of lipidadjusting therapy on prognosis of coronary heart disease(CHD). Methods:Z]86 cases of CHD with hyperlipidemia were treated with lipidadjusting drugs(treatment group) for average (3.10.7) years,comparing with 113 cases of CHD without lipidadjusting drugs at the same period(control group). Results:Z]The data showed that the serum TC,TG,LDLC and ApoB100 were significantly lowing,and the serum HDLC,ApoA1 were increasing(P<0.01) in treatment group after receiving lipidadjusting therapy.In addition,during the followup period,incidence of cardiac events in treatment group was 27.91%,along with observating duration being longer,the incidence was lowing gradually(P<005),but the morbidity of cardiac events in control group was 87.61%,and the longer of observating duration,the higher the incidence(P<001). Conclusions:Z]Longterm and effective lipidadjusting therapy exert a beneficial effect on the prognosis of patients with CHD.