| 氯霉素水杨酸搽剂微生物限度检查方法的验证 |
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| 引用本文： | 邓菲,宋莹. 氯霉素水杨酸搽剂微生物限度检查方法的验证[J]. 首都医药, 2014, 0(2): 55-56 |
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| 作者姓名： | 邓菲 宋莹 |
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| 作者单位： | 天津市水阁医院,300100 |
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| 摘 要： | 目的建立氯霉素水杨酸搽剂的微生物限度检查方法。方法参照《中国药典》2010版，采用5种阳性对照菌回收率试验测定其是否含抑菌成分。结果该品种对大肠埃希菌、枯草芽孢杆菌、金黄色葡萄球菌、白色念珠菌和黑曲霉均没有抑菌活性，细菌、霉菌和酵母菌数及控制茵的检查采用常规法进行。结论用该方法进行微生物限度检查可以客观地反映药物中微生物的污染状况，可用于该制剂微生物控制。
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| 关 键 词： | 氯霉素水杨酸搽剂 微生物限度检查法 常规法 |
Verification of the Method to Determine the Microbial Limit Test for Chloramphenicol Salicylic Acid Liniment |
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| Deng Fei,Song Ying. Verification of the Method to Determine the Microbial Limit Test for Chloramphenicol Salicylic Acid Liniment[J]. Capital Medicine, 2014, 0(2): 55-56 |
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| Authors: | Deng Fei Song Ying |
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| Affiliation: | Tianjin Shuige HospitaI,Tianjin(300100) China |
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| Abstract: | Method According to China Pharmcopoeia edition 2010,the antimicrobial effect of Chloramphenicol salicylic acid liniment was determined by recovery rate with 5 control trains.Result Antibacterial effect was not found against escherichia coli,bacillus subtilis,staphylococcus aureus,Candida albicans and Aspergillus niger.Conventional method was used for counting bacteria. Gonc lusion The method is sample and it can be used for qualitity control of Chloramphenicol salicylic acid liniment. |
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| Keywords: | Chloramphenicol Salicylic AcidLiniment Microbial Limit Test ConventionalMethod |
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