| α—人心房钠尿因子对离体豚鼠心肌收缩力和动作电位... |
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| 引用本文： | 吴伟建 夏强. α—人心房钠尿因子对离体豚鼠心肌收缩力和动作电位...[J]. 生理学报, 1991, 43(2): 195-198 |
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| 作者姓名： | 吴伟建 夏强 |
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| 摘 要： |
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| 关 键 词： | 心房钠泵因子 心肌 动作电位时程 |
Effect of alpha-human atrial natriuretic factor on isolated myocardial contractile force and action potential duration in guinea pigs] |
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| W J Wu,Q A Xia. Effect of alpha-human atrial natriuretic factor on isolated myocardial contractile force and action potential duration in guinea pigs][J]. Acta Physiologica Sinica, 1991, 43(2): 195-198 |
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| Authors: | W J Wu Q A Xia |
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| Affiliation: | Section of Physiology, Zhoushan Health School, Zhejiang. |
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| Abstract: | The effect of alpha-hANF on contractile force and action potential duration (APD) of isolated myocardium in guinea pig was investigated. At the level of 20 nmol/L and 40 nmol/L alpha-hANF, the contraction amplitude and rate of contraction phase decreased to a remarkable extent. And at 40 nmol/L, APDs were shortened significantly 20 min after alpha-hANF. The results suggest that there exists a direct inhibitory effect of alpha-hANF on myocardial contractile force and action potential duration. |
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