原发性肾小球疾病97例临床病理分析

目的: 探讨原发性肾小球疾病患者临床表现与病理之间的关系、肾活检的并发症及其临床意义。方法: 分析97例原发性肾小球疾病患者的临床表现、病理类型及肾活检资料。结果: 97例原发性肾小球疾病中,IgA肾病30例,系膜增生性肾小球肾炎26例,膜性肾病10例,局灶性节段性硬化性肾小球肾炎14例,IgM肾病2例,毛细血管内增生性肾小球肾炎1例,肾小球轻微病变8例,增生硬化性肾小球肾炎4例,新月体性肾小球肾炎2例。肾活检术后并发症:肉眼血尿3例,肾包膜下小血肿2例,无其它严重并发症。结论: 肾活检病理检查与临床密切结合,有助于原发性肾脏疾病正确诊断和治疗。肾穿刺术虽有一定并发症,但多不严重,是一项安全、简便的诊断操作。

Pathologic analysis of primary glomerular diseases:A report of 97 cases

Objective:To study the relationship between the clinical manifestations and pathologic type of primary glomerular disease,as well as the the complications of percutaneous renal biopsy and its significance.Methods:The clinical manifestications,pathologic type and safety of percutaneous renal biopsy in 97 cases of primary glomerular disease were analyzed.Results:Among the 97 cases of primary glomerular diseases,30 IgA nephropathy,26 mesangial proliferative glomerulonephritis,10 membranous nephropathy,14 focal segmental glomerulosclerosis,2 IgM nephropathy,1 endocapillary proliferative glomerulonephritis,8 minimal change nephrosis,4 proliferative sclerosing glomerulomephritis and 2 crescentic glomerulonephritis.Complications occurred in five cases,three had naked eye hematuria,two perirenal hematoma,and no other serious complications.Conclusions:Combination of pathologic and clinical examination help to accurate diagnosis and therapy.Though the percutaneous renal biopsy has some slight complication,it is still a safe,simple and convenient diagnostic procedure.