| 非心血管药物所致尖端扭转型室性心动过速的分类与处理 |
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| 引用本文： | 袁景,丁仲如. 非心血管药物所致尖端扭转型室性心动过速的分类与处理[J]. 药学服务与研究, 2006, 6(6): 443-445 |
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| 作者姓名： | 袁景 丁仲如 |
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| 作者单位： | 1. 吉林省通化市中心医院心血管内科,通化,134000
2. 第二军医大学长海医院心血管内科,上海,200433 |
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| 摘 要： | 目的：介绍引起QT间期延长及尖端扭转型室性心动过速（简称室速）的非心血管药物的种类和致病机制，以引起临床医生的重视。方法：对国内外相关文献进行综合、归纳。结果：许多非心血管药物可引起QT间期延长及尖端扭转型室速，包括抗微生物药、抗组胺药、三环类抗抑郁药、抗精神病药和胃肠动力药等。结论：了解导致这种较为罕见且严重的心带失常药物的种类及发病机制，对预防和正确治疗极为重要。
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| 关 键 词： | 非心血管药物 心动过速,室性 药物副反应报告系统 综述 |
| 文章编号： | 1671-2838(2006)06-0443-03 |
| 收稿时间： | 2006-05-08 |
| 修稿时间： | 2006-10-28 |
Torsades de pointes induced by noncardiovascular drugs |
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| YUAN Jing,DING Zhong-ru. Torsades de pointes induced by noncardiovascular drugs[J]. Pharmaceutical Care and Research, 2006, 6(6): 443-445 |
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| Authors: | YUAN Jing DING Zhong-ru |
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| Affiliation: | 1. Department of Cardiovasology, Central Hospital of Tonghua, Tonghua 134000, China; 2. Department of Cardiovasololgy,Changhai Hospital, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Objective: To introduce the pathogenesis of QT prolongation and torsades de pointes(TDP) induced by noncar-diovascular drugs and the classes of the drugs. Methods: The newest related literature at home and abroad was collected and summarized. Results: Many noncardiovascular drugs could cause QT prolongation and TDP, including antimicrobials, antihis-tarainics, tricyclic antidepressants, antipsychotics and gastrointestinal kinetogenic drugs, etc. Conclusion: It is important to be aware of the classes of drugs causing TDP and their pathogenic mechanism, which may be helpful to make an appropriate treatment strategy. |
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| Keywords: | noncardiovascular drugs tachycardia, ventrieular adverse drug reaction reporting systems review |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
