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| 水性CdTe量子点在肝癌细胞标记中的应用 | |
| 引用本文： | 张婷婷,曾若生,罗泽宇,代国章.水性CdTe量子点在肝癌细胞标记中的应用[J].应用化工,2011,40(5):748-753. |
| 作者姓名： | 张婷婷 曾若生 罗泽宇 代国章 |
| 作者单位： | 1. 湖南农业大学作物种质创新与资源利用重点实验室,湖南长沙410128;贵州师范大学化学与材料科学学院,贵州贵阳550001 2. 贵州师范大学化学与材料科学学院,贵州贵阳,550001 3. 湖南省农业科学院杂交水稻研究中心,湖南长沙,401125 4. 北京理工大学微纳技术中心,北京,100081 |
| 基金项目： | 国家自然科学基金青年基金 |
| 摘 要： | 采用一种简单的合成方法,用空气中稳定性良好的亚碲酸钠为前体,合成了高质量的CdTe量子点,发射范围从520～620 nm可调,最佳实验条件下发光效率达40%以上。用叶酸修饰的CdTe量子点作为荧光探针,成功标记肝癌细胞,实验结果表明,通过叶酸偶联的CdTe量子点,能有效进入肿瘤细胞内部。 |
| 关 键 词： | CdTe量子点 叶酸 荧光探针 细胞标记 |
Aqueous CdTe quantum dots for labeling liver cancer cells |
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| ZHANG Ting-ting,ZENG Ruo-sheng,LUO Ze-yu,DAI Guo-zhang.Aqueous CdTe quantum dots for labeling liver cancer cells[J].Applied chemical industry,2011,40(5):748-753. | |
| Authors: | ZHANG Ting-ting ZENG Ruo-sheng LUO Ze-yu DAI Guo-zhang |
| Affiliation: | ZHANG Ting-ting1,2,ZENG Ruo-sheng2,LUO Ze-yu3,DAI Guo-zhang4 (1.Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization,Hunan Agricultural University,Changsha 410128,China,2.School of Chemistry and Material Science,Guizhou Normal University,Guiyang 550001,3.Hunan Academy of Agricultural Sciences,Hunan Hybrid Rice Research Center,Changsha 410125,4.Micro-Nano Technology Center,Beijing Institute of Technology,Beijing 100081,China) |
| Abstract: | A simple route of aqueous synthesis of highly luminescent CdTe quantum dots(QDs) was reported using stable Na2TeO3 in air as the precursor.The emission range of CdTe quantum dots was 520～620 nm and photoluminescence quantum yield(PL QY) was up to 40% under the best experimental conditions.Liver cancer cells were labeled using folic acid(FA) modified CdTe quantum dots as a fluorescent probe,which indicated that folic acid conjugated CdTe QDs could enter liver cancer cells efficiently. |
| Keywords: | CdTe quantum dots folic acid fluorescent probe cell-labeling |
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