| 聚对硝基苯偶氮间苯二酚修饰电极伏安法测定多巴胺 |
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| 引用本文： | 林丽清,郑艳洁,陈敬华,林新华.聚对硝基苯偶氮间苯二酚修饰电极伏安法测定多巴胺[J].化学研究,2007,18(2):47-49. |
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| 作者姓名： | 林丽清 郑艳洁 陈敬华 林新华 |
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| 作者单位： | 福建医科大学,药学院药物分析系,福建,福州,350004 |
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| 基金项目： | 国家自然科学基金资助项目(20675015)，福建省卫生厅青年基金资助项目(2006111) |
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| 摘 要： | 采用循环伏安法研究了多巴胺(DA)在聚对硝基苯偶氮间苯二酚(p-nitrobenzenazo resorcinol,简称NBAR)膜修饰电极上的电化学行为,用差示脉冲伏安法对多巴胺的含量进行测定.结果表明,聚NBAR膜修饰电极对DA有明显的电催化作用.在pH4.0的磷酸盐缓冲液中,氧化峰电流与DA浓度在5.0×10-6~8.0×10-4mol/L范围内呈良好的线性关系,检测限为6.0×10-7mol/L.修饰电极可有效消除针剂中其它组分对DA测定的干扰,已用于实际样品DA含量的测定,结果令人满意.
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| 关 键 词： | 聚对硝基苯偶氮间苯二酚 修饰电极 电化学行为 循环伏安 多巴胺 |
| 文章编号： | 1008-1011（2007）02-0047-03 |
| 修稿时间： | 2007-03-06 |
Determination of Dopamine Using Poly(p-nitrobenzenazo resorcinol) Modified Glassy Carbon Electrode with Cyclic Voltammetric Method |
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| LIN Li-qing,ZHENG Yan-jie,CHEN Jing-hua,LIN Xin-hua.Determination of Dopamine Using Poly(p-nitrobenzenazo resorcinol) Modified Glassy Carbon Electrode with Cyclic Voltammetric Method[J].Chemical Research,2007,18(2):47-49. |
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| Authors: | LIN Li-qing ZHENG Yan-jie CHEN Jing-hua LIN Xin-hua |
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| Affiliation: | Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350004, Fujian, China |
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| Abstract: | The electrochemical behavior of dopamine (DA) on poly(p-nitrobenzenazo resorcinol)(NBAR) film modified electrode was studied by cyclic voltammetry(CV), while the determination of DA was measured by differential pulse voltammetry (DPV). It was found that the modified electrode showed excellent electrocatalytic characteristics for DA. In pH 4.0 phosphate buffer solution, the relationship between oxidation peak current and the concentration of DA is linear in the range of 5.0×10-6～8.0×10-4mol/L. The detection limit is 6.0×10-7 mol/L. The interference of other components could be efficiently eliminated on the modified electrode. This method can be used for the determination of DA in real sample with satisfactory results. |
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| Keywords: | poly(p-nitrobenzenazo resorcinol) modified electrode electrocatalytic behavior cyclic voltammetry dopamine |
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