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慢性阻塞性肺病并发呼吸衰竭病人早期肠内营养支持的临床研究
引用本文:张琳,钟明媚,郝明伟.慢性阻塞性肺病并发呼吸衰竭病人早期肠内营养支持的临床研究[J].肠外与肠内营养,2009,16(2).
作者姓名:张琳  钟明媚  郝明伟
作者单位:安徽医科大学第三附属医院ICU,安徽合肥,230061
摘    要:目的:观察慢性阻塞性肺病(COPD)并发呼吸衰竭病人EEN支持的疗效.方法:63例COPD并发呼吸衰竭病人在开始机械通气时,随机分为EEN组32例和延迟EN(DEN)组31例,比较两组病人营养支持2周后的各项生化指标、机械通气时间、并发症和病死率等.结果:治疗2周后,EEN组病人血清总蛋白、ALB、PA和Hb水平无明显下降(P>0.05),但DEN组上述指标较治疗前明显下降,差异有显著性意义(P<0.05).EEN组与DEN组相比,机械通气时间明显缩短,腹胀、腹泻、消化道出血、二重感染、肝功能损害、高血糖等发生率明显降低,病死率亦有所降低,差异有显著性意义(P<0.05).结论:COPD并发呼吸衰竭病人行EEN支持治疗,能改善病人的营养状况,减少并发症,缩短机械通气时间和降低最终病死率,是较好的营养支持方式.

关 键 词:慢性阻塞性肺病  呼吸衰竭  早期肠内营养

Clinical research of early enteral nutrition support in COPD complicated with respiratory failure patients
ZHANG Lin,ZHONG Ming-mei,HAO Ming-wei.Clinical research of early enteral nutrition support in COPD complicated with respiratory failure patients[J].Parenteral & Enteral Nutrition,2009,16(2).
Authors:ZHANG Lin  ZHONG Ming-mei  HAO Ming-wei
Affiliation:Insensive Care Unit;the Third Affiliated Hospital of Anhui Medical University;Hefei 230061;Anhui;China
Abstract:Objective:To investigate the curative effect of early enteral nutrition support in patients with COPD complicated with respiratory failure.Methods: When mechanical ventilation began,63 patients in the acute phase of COPD complicated with respiratory failure were divided into two groups: the early enteral nutrition group(EEN group,n=32) or the delayed enteral nutrition group(DEN group,n=31).After two weeks,the nutritional indexes,the times of mechanical ventilation,the incidence of complication and the morta...
Keywords:Chronic obstructive pulmonary disease  Respiratory failure  Early enteral nutrition  
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