Resolution of hepatitis B virus-related membranoproliferative glomerulonephritis after orthotopic liver transplantation |
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| Authors: | Albert Quan Anthony Portale Steven Foster Joel Lavine |
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| Affiliation: | (1) Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, 75235-9063 Dalas, Texas, USA;(2) Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA;(3) Department of Pediatrics, University of California, San Francisco, California, USA;(4) Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA |
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| Abstract: | The most well-described renal disease associated with hepatitis B virus (HBV) infection is membranous glomerulonephritis; membranoproliferative glomerulonephritis is described much less frequently. The course of HBV-associated renal disease after liver transplantation has not been described to date. We present a 15-year-old girl with HBV-associated membranoproliferative glomerulonephritis and end-stage liver disease, in whom, after cadaver liver transplantation, clinical and histological resolution of renal disease was observed. Resolution was associated with diminution of circulating HBV surface antigen levels. |
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| Keywords: | Membranoproliferative glomerulonephritis Hepatitis B virus Liver transplantation |
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