| 2-重氮乙酰乙酸对硝基苄酯的合成 |
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| 引用本文： | 王淑娟,孙楠,莫卫民,胡宝祥.2-重氮乙酰乙酸对硝基苄酯的合成[J].精细化工中间体,2007,37(2):37-38. |
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| 作者姓名： | 王淑娟 孙楠 莫卫民 胡宝祥 |
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| 作者单位： | 浙江工业大学,化学工程与材料学院,浙江,杭州,310014 |
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| 基金项目： | 浙江省科技厅计划项目资助(2006C31036)。 |
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| 摘 要： | 以对硝基苄醇与乙酰乙酸甲酯为起始原料,通过酯交换反应得到乙酰乙酸对硝基苄酯,进一步以叠氮化钠为重氮化试剂,甲磺酰氯催化下,合成2-重氮乙酰乙酸对硝基苄酯,两步反应总收率为92.6%。
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| 关 键 词： | 2-重氮乙酰乙酸对硝基苄酯 乙酰乙酸对硝基苄酯 合成 |
| 文章编号： | 1009-9212（2007）02-0037-02 |
| 修稿时间： | 2007-01-04 |
Synthesis of p-Nitrobenzyl 2-diazoacetoacetate |
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| WANG Shu-juan,SUN Nan,MO Wei-min,HU Bao-xiang.Synthesis of p-Nitrobenzyl 2-diazoacetoacetate[J].Fine Chemical Intermediates,2007,37(2):37-38. |
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| Authors: | WANG Shu-juan SUN Nan MO Wei-min HU Bao-xiang |
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| Affiliation: | College of Materials Science and Chemical Engineering, ZhejiangUniversityofTechnology, Hangzhou310014, China |
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| Abstract: | p-Nitrobenzyl-2-diazoacetoacetate was synthesized by p-Nitrobenzyl acetoacetate and azide sodium in the presence of methyl sulfonylchloride. The main intermediate of p-Nitrobenzyl acetoacetate was synthesized by transesterification reaction with methyl acetoacetate and 4-nitrobenzyl alcohol. The overall yield obtained was 92.6 %. |
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| Keywords: | p-nitrobenzyl-2-diazoacetoacetate p-nitrobenzyl acetoacetate synthesis |
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