| 嗜碱粒细胞组胺释放试验检测抗高亲和力IgE抗体及其受体 |
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| 引用本文： | 刘荣卿,孙仁山.嗜碱粒细胞组胺释放试验检测抗高亲和力IgE抗体及其受体[J].重庆医学,2001,30(1):27-28. |
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| 作者姓名： | 刘荣卿 孙仁山 |
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| 作者单位： | 第三军医大学西南医院皮肤科 |
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| 摘 要： | 目的 探讨慢性荨麻疹的发生机制。方法 用嗜碱粒细胞组胺释放试验，检测慢性特发性荨麻疹患者的血清组胺释放活性。结果 32例中，有15例（46．9％）患者血清组胺释放活性增高，提示FcεR1抗IgE自身抗体的存在。结论 部分慢性荨麻疹的发生与自身免疫机制有关。
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| 关 键 词： | 慢性特发性荨麻疹 嗜碱粒细胞组胺释放试验 自身抗体 IgE抗体 受体 |
| 文章编号： | 1000-7911(2001)01-0027-02 |
Significance of basophil histamine release assays in chronic urticaria |
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| LIU Rong-qing,Sun Ren-shan.Significance of basophil histamine release assays in chronic urticaria[J].Chongqing Medical Journal,2001,30(1):27-28. |
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| Authors: | LIU Rong-qing Sun Ren-shan |
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| Abstract: | Objective To Investigate the pathogenesis of chronic idiopathic urticaria.Methods Basophil histamine release assay was utilized.Result 15 of 32 cases(46.9%)had increased serum histamine releasing activities. This implied that anti-FcεR1 and anti-IgE autoantibodies existed in the sera of some patients with chronic idiopathic urticaria.Conclusion It suggested that autoimmunity might take part in the occurrence of some patients with chronic idiopathic urticaria. |
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| Keywords: | chronic idiopathic urticaria autoantibody basophil histamine release assay |
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