TiO2 as a Reusable Catalyst for the One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones under Solvent‐Free Conditions |
| |
| Authors: | Mohammad Zaman Kassaee Hassan Masrouri Farnaz Movahedi Reza Mohammadi |
| |
| Affiliation: | 1. Department of Chemistry, Tarbiat Modares University, P.?O. Box 14155‐4838, Tehran, Iran, (phone: +98‐912‐1000392;2. fax: +98‐21‐88006544) |
| |
| Abstract: | An efficient solvent‐free method for the synthesis of various 3,4‐dihydropyrimidin‐2(1H)‐ones using TiO2 as a recyclable heterogeneous catalyst is described. Compared to known methods, satisfactory results are obtained with excellent yields, short reaction times, and simplicity in the experimental procedure. |
| |
| Keywords: | Biginelli reaction Pyrimidin‐2(1H)‐ones, 3,4‐dihydro‐ Solvent‐free chemistry Catalysis Multicomponent reactions |
|
|
