益生菌治疗肠易激综合征的临床疗效

目的：探讨益生菌治疗肠易激综合征（IBS）的安全性和有效性。方法：收集本院本科2005年5月到2011年6月的肠易激综合征患者240名，分为益生菌组（用益生菌＋常规治疗，120例），对照组（常规治疗，120例），比较两组疗效及不良反应。结果：治疗3个疗程后，益生菌组115例有效，有效率95．83％，常规治疗组97例有效，有效率80．83％（P〈0．05），未见不良反应。结论：益生菌能有效缓解IBS患者的症状且不良反应较少。

Clinical efficacy of probiotics in patients with irritable bowel syndrome

Objective： To investigate the safety and efficacy of probiotics in patients with irritable bowel syndrome （IBS）. nethods：A total of 240 patients with IBS who presented to our department between May 2005 and June 2011 were included and assigned to the probiotics groups （treated on probiotics and conventional therapy, n = 120） or the control group （conventional therapy alone, n = 120）. Therapeutic efficacy and adverse events were compared between groups. Results：After 3 courses of treatment, 115 cases of the probiotic group showed improvement （ rate of response ： 95.83% ）, compared with 97 cases （rate of response ： 80.83% ） of the control group （P 〈 0.05）. No adverse events were found in either group. Conclusion：Probiotics can effectively alleviate the symptoms of IBS and are well-tolerated.