前列腺癌内分泌治疗后复发的MRI研究

目的探讨前列腺癌内分泌治疗后复发的MR I征象。方法10例经临床诊断证实的前列腺癌内分泌治疗后复发的病人,在内分泌治疗过程中肿瘤复发前后都进行了MR I检查。对2次MR I图像中前列腺T2信号、体积变化、对周围组织侵犯、扫描范围内的骨转移和淋巴结转移等情况进行对比分析。结果与复发前对比,前列腺体积增大的有7例,体积未见明显变化的有3例。复发后新出现的周围组织侵犯包括精囊腺(3例)、膀胱(2例)、直肠(1例)、盆底肌(1例)。复发后扫描范围内(骨盆至髂血管分叉水平)原有骨转移病灶进展的有3例,新出现转移灶的有4例。新出现髂血管旁肿大淋巴结的有4例,腹股沟肿大淋巴结的有2例。结论MR I检查能提供有助于诊断内分泌治疗后肿瘤复发的多方面影像信息。

MRI Characteristics of Recurrent Prostate Cancer after Endocrinotherapy

Objective To investigate MRI characteristics of recurrent prostate cancer after endocrinotherapy.Methods Recurrent prostate cancer after endocrinotherapy was diagnosed clinically in 10 cases.MRI examinations were performed before and after recurrence of tumors.T_2 signal intensity and morphological changes of the prostate,involvement of pelvic tissues,metastasis of bone and lymph metastasiswere analyzed.Results The prostates enlarged in 7 patients after recurrence and maintained the same size in the other three.The pelvictissues,including seminal vesicle,bladder,rectal and obturator internus,were involved in 7 patients after recurrence.Metastasis of bone and lymph node progressed in 7 and 9 patients,respectively,but T_2 signal differences were unremarkable between recurrent regions and otherregions.Conclusion MRI examination can provide sufficient radiologic information in the diagnosis of recurrence of prostate cancer afterendocrinotherapy.