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Myatrophische Lateralsklerose kombiniert mit Degeneration im Thalamus und der Substantia nigra
Authors:K Kosaka  P Mehraein
Affiliation:(1) Max-Planck-Institut für Psychiatrie, Kraepelinstr. 2, D-8000 München 40, Bundesrepublik Deutschland;(2) Abteilung für Neuropathologie der Medizinischen Hochschule Hannover, D-3000 Hannover, Bundesrepublik Deutschland;(3) Present address: Psychiatric Research Institute of Tokyo, 2-1-8 Kamikitazawa, Setagaya-ku, Tokyo, Japan
Abstract:Summary A 40-year-old man suffering from amyotrophic lateral sclerosis with symmetrical degeneration of the thalamus and the substantia nigra is reported. The distribution pattern of the thalamic degeneration in the present case was characteristic in that the Nucleus centralis was the severest affected of the thalamic nuclei. As far as we know, there is no such case of amyotrophic lateral sclerosis in the literature. Nosologically, this case may represent a form of combined heredosystemic degeneration.
Keywords:Amyotrophic lateral sclerosis  Thalamic degeneration  Nigral degeneration  Combined system degeneration
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