2型糖尿病患者下肢血管病变发生率及危险因素分析

目的了解2型糖尿病（T2DN）患者下肢血管病变（PVD）发生率及相关危险因素。方法对318例T2DM患者进行进行超声多普勒扫描仪检查，比较下肢血管病变组与无下肢血管病变组一般情况及生化指标间的差异。结果67．2％（205／318）患者超声多普勒检查提示有下肢血管病变。年龄、病程、糖化血红蛋白（HbAlc）、血脂、血压和体质量指数（BMI）在下肢血管病变组显著高于无下肢血管病变组（P〈0．01）。结论2型糖尿病患者下肢血管病变发生率高，高血压、高血脂、高血糖是其独立危险因素，严格控制血压、血脂、血糖有利于预防和减少下肢血管病变的发生。

Incidence and risk factors of the vascular disease in lower limbs of patients with type 2 diabetes

Objective To investigate the incidence and the risk factors of the vascular disease in lower limbs of patients with type 2 diabetes(T2DM).Methods To retrospectively analyze 318 cases with T2DM patients.All the patients were checked on both lower limbs by color ultrasonic Doppler.The differences of ordinary and biochemical indicators between PVD group and non-PVD group were compared.Results There were 67.2％ (205/318) patients who had vascular disease in lower limbs with type 2 diabetes.Age,course of disease,HbAlC,TC,TG,SBP,DBP and BMI in PVD group were significantly higher than those in non-PVD group( P ＜ 0.01 ).Conclusion There was higher incidence of the vascular disease in lower limbs of patients with type 2 diabetes.And the independent risk factors were hypertension,hyperglycemia,hyperlipemia.It could help to prevent the development of lower limb blood vessel pathological changes in DM patients by controlling the levels of blood pressure,lipid and blood sugar strictly.