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Normal Tissue Complication Probability Modelling for Toxicity Prediction and Patient Selection in Proton Beam Therapy to the Central Nervous System: A Literature Review
Affiliation:1. Proton Clinical Outcomes Unit, The Christie NHS Foundation Trust, Manchester, UK;2. Division of Clinical Cancer Science, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK;3. Clinical Oncology, Proton Beam Therapy Centre, The Christie NHS Foundation Trust, Manchester, UK;4. Department of Radiotherapy Related Research, The Christie NHS Foundation Trust, Manchester, UK;5. University of Florida Department of Radiation Oncology, Jacksonville, Florida, USA;7. Institute of Medical Physics, School of Physics, University of Sydney, Sydney, New South Wales, Australia;11. NHS England National Clinical Lead Proton Beam Therapy, UK;1. North Middlesex University Hospital NHS Trust, London, UK;2. South West Sydney Clinical Campuses, UNSW Medicine & Health, UNSW Sydney, Sydney, Australia;3. Ingham Institute for Applied Medical Research, Liverpool, Australia;4. Barnet Enfield & Haringey Mental Health NHS Trust, London, UK;1. Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Sidney Kimmel Cancer Center, Baltimore, Maryland, USA;2. Department of Surgery, Johns Hopkins University School of Medicine, Sidney Kimmel Cancer Center, Baltimore, Maryland, USA;3. Department of Oncology, Johns Hopkins University School of Medicine, Sidney Kimmel Cancer Center, Baltimore, Maryland, USA;4. Department of Radiation Oncology, Northwell Health, New Hyde Park, New York, USA;1. Department of Radiation Medicine, Lowell General Hospital, Lowell, MA, USA;2. Department of Radiation Oncology, Beacon Hospital, Sandyford, Dublin, Ireland;3. Department of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, USA;1. Department of Oncology, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, UK;2. Department of Surgery and Cancer, Imperial College London, London, UK;3. Department of Ageing and Health, St Thomas'' Hospital, Guys and St Thomas'' NHS Foundation Trust, London, UK;4. Division of Health and Social Care Research, King''s College London, London, UK;1. Department of Oncology, Colchester Hospital, Colchester, UK;2. University of Cambridge, Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
Abstract:
Keywords:Clinical implementation of normal tissue complication probability models  normal tissue complication probability models for patient selection in proton therapy to the brain  normal tissue complication probability models for toxicity prediction in proton beam therapy  proton beam therapy in brain malignancies  radiation-induced secondary tumours
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