Rapid and efficient synthesis of optically active pyrazoles under solvent-free conditions |
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| Authors: | JS Yadav BVS Reddy P Naga Lakshmi AC Kunwar |
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| Affiliation: | a Division of Organic Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India
b Centre for Nuclear Magnetic Resonance, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
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| Abstract: | 2-Formyl glycals undergo rapid condensation with arylhydrazines under solvent-free conditions to give the corresponding optically pure 4-substituted pyrazoles in good yields with high selectivity. The stereochemistry of the products was assigned by various NMR experiments. |
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| Keywords: | Arylhydrazines 2-Formyl glycals Microwaves Pyrazoles |
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