| 多部位发生的上皮样血管内皮瘤2例报道及文献复习 |
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| 引用本文： | 张芬,刘艳辉,庄恒国,罗东兰,骆新兰. 多部位发生的上皮样血管内皮瘤2例报道及文献复习[J]. 临床与实验病理学杂志, 2008, 24(4) |
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| 作者姓名： | 张芬 刘艳辉 庄恒国 罗东兰 骆新兰 |
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| 作者单位： | 广东省人民医院病理医学部病理科,广州,510080;广东省人民医院病理医学部病理科,广州,510080;广东省人民医院病理医学部病理科,广州,510080;广东省人民医院病理医学部病理科,广州,510080;广东省人民医院病理医学部病理科,广州,510080 |
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| 摘 要： | 目的 探讨多部位发生的上皮样血管内皮瘤(EHE)的临床病理学特征.方法 回顾性复习2例多部位发生的血管内皮瘤的临床资料、组织学形态和免疫学表型,并复习文献.结果 2例均为女性,年龄分别为24和37岁,CT示双肺及肝弥漫结节影.病理学检查发现肝和肺结节的镜下形态相同,即在黏液样的间质背景中可见条索样、小巢状或单个散在分布的上皮样瘤细胞,瘤细胞有明显异型性,伴胞质内管腔形成,腔内偶见红细胞.免疫组织化学染色显示:瘤细胞表达内皮标记(CD34、CD31和F8),不表达CK、CD68、ER、PR.结论 上皮样血管内皮瘤是一种少见的低度恶性血管肿瘤,多部位同时发生者容易被误诊.上皮样血管内皮瘤的临床表现和生物学行为因其发生部位不同而有较大的差异.
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| 关 键 词： | 上皮样血管内皮瘤 肝肿瘤 肺肿瘤 免疫组织化学 |
Epithelioid hemangioendothelioma with multiple organ involvement:a report of two cases and review of literature |
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| ZHANG Fen,LIU Yan-hui,ZHUANG Heng-guo,LUO Dong-lan,LUO Xin-lan. Epithelioid hemangioendothelioma with multiple organ involvement:a report of two cases and review of literature[J]. Chinese Journal of Clinical and Experimental Pathology, 2008, 24(4) |
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| Authors: | ZHANG Fen LIU Yan-hui ZHUANG Heng-guo LUO Dong-lan LUO Xin-lan |
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| Affiliation: | Department of Pathology;Guangdong Provincial People's Hospital;Guangzhou 510080;China |
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| Abstract: | Purpose To study the morphological and clinical features of epithelioid hemangioendothelioma with multiple organ involvement.Metheods Two cases of EHE with multiple organ involvement were examined by light microscopy and immunohistochemistry.Results The both patients were women,24 and 37 years old,respectively.CT scan revealed numerous small lung and liver nodules.Pathologic findings showed a hypocellular lesion with scattered aggregates,cords,and individual tumor cells within an abundant background of stro... |
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| Keywords: | epithelioid hemangioendothelioma liver neoplasms lung neoplasms |
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