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耐甲氧西林金黄色葡萄球菌的目标性监控与分析
引用本文:杨怀,郑金鼎,徐艳,王建怡,牟霞,罗湘蓉,袁军,陈京.耐甲氧西林金黄色葡萄球菌的目标性监控与分析[J].中华医院感染学杂志,2012,22(7):1461-1463.
作者姓名:杨怀  郑金鼎  徐艳  王建怡  牟霞  罗湘蓉  袁军  陈京
作者单位:1. 贵州省人民医院医院感染管理科,贵州贵阳,550002
2. 贵州省人民医院医院院办,贵州贵阳,550002
3. 贵州省人民医院医院中心实验室,贵州贵阳,550002
摘    要:目的 了解临床耐甲氧西林金黄色葡萄球菌的分离及耐药性,探索耐甲氧西林金黄色葡萄球菌感染病例的监控措施.方法 对2010年医院临床分离的病原菌进行目标性监测,统计出耐甲氧西林金黄色葡萄球菌的株数以及耐药性,并对临床耐甲氧西林金黄色葡萄球菌感染病例实施监控.结果 全年检测结果发现,共分离出金黄色葡萄球菌334株,耐甲氧西林金黄色葡萄球菌50株,检出率为14.97%;对抗菌药物耐药率较高;全院未发生耐甲氧西林金黄色葡萄球菌的暴发和流行.结论 耐甲氧西林金黄色葡萄球菌分离株数较多,耐药率较高,应该加强临床合理使用抗菌药物的管理,并对耐甲氧西林金黄色葡萄球菌感染病例实施监控,预防和减少多药耐药菌的产生,控制医院感染.

关 键 词:耐甲氧西林金黄色葡萄球菌  目标性监测  分析

Targeted monitoring of methicillin-resistant Staphylococcus aureus
YANG Huai , ZHENG Jin-ding , XU Yan , WANG Jian-yi , MU Xia , LUO Xiang-rong , YUAN Jun , CHEN Jing.Targeted monitoring of methicillin-resistant Staphylococcus aureus[J].Chinese Journal of Nosocomiology,2012,22(7):1461-1463.
Authors:YANG Huai  ZHENG Jin-ding  XU Yan  WANG Jian-yi  MU Xia  LUO Xiang-rong  YUAN Jun  CHEN Jing
Affiliation:(People’s Hospital of Guizhou province,Guiyang,Guizhou 550002,China)
Abstract:OBJECTIVE To understand the isolation and drug resistance of methicillin-resistant Staphylococcus aureus(MRSA) and explore measures for monitoring of methicillin-resistant S.aureus infection.METHODS Targeted monitoring of clinical isolates was carried out in 2010,statistical analysis of MRSA isolates and the drug resistance was conducted,and the patients with methicillin-resistant S.aureus infections were monitored.RESULTS There were totally 334 strains of S.aureus isolated with the detection rate of 14.97%;the drug resistance rate was high;the outbreak and prevalence of MRSA did not occurred.CONCLUSION Since there are so many MRSA strains isolated with high resistance rate,it is necessary to strengthen the clinical management of rational use of antibiotics and MRSA infections including implementing the monitoring,preventing and reducing the multidrug-resistant strains and controlling the hospital infections.
Keywords:Methicillin-resistant Staphylococcus aureus  Targeted monitoring  Analysis
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