腓骨肌萎缩症的临床及电生理研究：附32例报告

本文报告32例腓骨肌萎缩症(PMA)患者的临床及肌电图(EMG)和神经传导速度(NCV)的改变。其中20例PMA患者的感觉神经传导速度(SNCV)减慢,正中神经SNCV:拇指到腕平均为21.0m/s,中指到腕平均22.7m/s、末端潜伏期(ML)平均为7.3ms;胫后神经SNCV:(足母)趾到踝平均为22.2m/s,ML平均为8.1ms,符合PMA Ⅰ型。另外12例患者的SNCV正常或轻度减慢,正中神经SNCV:拇指到腕平均为41.0m/s,中指到腕平均为47.0m/s,ML平均为3.2ms,胫后神经SNCV:(足母)趾到踝平均32.5m/s,ML平均为4.8ms,符合PMA Ⅱ型。二型NCV改变差异非常显著(P<0.01)。6例腓肠神经活检,5例符合NCV分型.提示详细的NCV检查是诊断本病重要而易行的手段。

Clinical electrophysiological studies of peroneal muscular atrophy--report of 32 cases

Clinical, electromyography (EMG) and nerve conduction velocity (NCV) features of 32 cases with peroneal muscular atrophy (PMA) are reported.Twenty of the cases showed remarkably slow NCV: median SNCV (Fing 1-W) X = 21.0 m/s, (Fing 3-W) X=22.7 m/s, motor latency (ML) X=7.3 ms; tibial SNCV (hallux-ankle) X = 22.2 m/s and ML = X = 8.1 ms, which were consistent with Type 1 PMA. Twelve cases showed normal or moderately slow NCV: .median SNCV (Fing 1-W) X = 41.9 m/s, (Fing 3-W) X= 47.0 m/s and ML X=3.2 ms; tibial SNCV (halluxankle) X = 32.5 m/s and ML X=4.8 ms which were consistent with Type 2 PMA. The difference between these two groups was very significant (P<0.01). Sural nerve biopsy performed in 6 cases showed that 5 corresponded with NCV classification. We conclude that careful NCV examination is necessary for classification of PMA.