影响胃癌根治术术后生存期的多因素分析

目的为了尽可能延长胃癌根治术术后患者生存期,多因素分析影响患者预后的危险因素。方法采取随机数字表法于2011年1月~2013年12月来我院治疗的胃癌根治术术后患者中抽取81例作为研究对象,回顾性分析入组患者的临床资料,通过多因素分析影响患者生存期的相关因素。结果研究结果显示,通过单因素分析发现影响胃癌根治术术后患者5年生存率的危险因素包括术后接受化疗与否、肿瘤的分化程度、肿瘤浸润程度、肿瘤体积、淋巴结是否转移及TNM分期(P0.05),而行多因素Logistic回归分析发现肿瘤分化程度、淋巴结转移程度、肿瘤TNM分期是影响胃癌根治术术后患者5年生存率的独立影响因素。结论胃癌根治术术后患者生存期受多因素影响,其中肿瘤分化程度、淋巴结转移程度、肿瘤TNM分期是影响患者预后的独立影响因素,临床必须予以重点关注。

Multivariate analysis of survival time after gastrectomy of stomach neoplasms

Objective To prolong the survival time of patients after gastrectomy for gastric cancer as much as possible,multivariate analysis was performed to investigate the risk factors of prognosis. Methods 81 cases of postoperative gastric cancer patients who had been treated in our hospital from January 2011 to December 2013 were selected as subjects using random number table. The clinical data of the enrolled patients were retrospectively analyzed. Factors that affecting survival time were investigated using multivariable analysis. Results Univariate analysis showed that the risk factors affecting the 5-year survival rate of patients undergoing gastrectomy included postoperative chemotherapy, tumor differentiation, tumor infiltration, tumor volume, lymph node metastasis, and TNM stages (P<0.05). Multivariate Logistic regression analysis revealed that tumor differentiation, lymph node metastasis, and tumor TNM stages were independent factors that influenced the 5-year survival rate of patients after gastrectomy. Conclusion The survival time of patients after gastrectomy is affected by many factors, among which the degree of tumor differentiation, lymph node metastasis,and the TNM stage of tumors are independent factors influencing the prognosis of patients, which is worth clinical attention.