应用核素心室造影研究甲亢患者左右心室收缩与舒张功能变化

应用核素心室造影对５０例甲亢患者进行左右心室收缩与舒张功能测定，结果左心室ＥＦ、ＳＶ比正常人减低（Ｐ＜０．０５），但ＣＯ反比正常人增高（Ｐ＜０．０１）；左心室ＰＦＲ亦减低（Ｐ＜０．０５），但ＰＥＲ却无明显减低（Ｐ＞０．０５）．右心室ＥＦ、ＰＥＲ、ＰＦＲ均有明显减低（Ｐ＜０．０１）。其中，３０例经心肺阻抗血流图检测结果与核素心室造影测定的结果相符。显示甲亢患者有心室功能受损明显，尤以右心室射血期最为显著。左室ＰＥＲ并未随左室ＰＦＥ的下降而减低，ＣＯ反而增加。甲亢（３０例）经过治疗症状控制后，复查左右心室功能均见ＥＦ、ＰＥＲ、ＰＦＲ明显升高，与治疗前相比有显著性差异。

Assessment of ventricular function by radionuclide ventriculography in hyperthyroidism

Left ventricular(LV) and right ventricular(RV) function were determined using radionuclide ventriculography in 50 patients with hyperthyroidism. LVEF, LVPFR,SV of the hyperthyroidism group were decreased in comparison with the normal group (P<0.01), whereas CO of the hyperthyroidism patients were higher than that of normal (P<0.01). Except LVPER, the LVEF, SV had significant difference between two groups. Compared to normal group, RVEF, RVPER, RVPFR were also decreased(P<0.01). Besides 30 cases of the hyperthyroidism were examined by impedancecardiogram(ICG) and impedance pulmonary rheogram(IPR), all showed closely correlation with the parameters determined by ventyiculography. There was the involvment of right ventricular function insufficiency,especially in ejection phase.When compared with pre-therapy and pos-therapy cases showed significant improvement in EF, PER, PFR of left and right ventriculars.